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Metoprolol occurs as selective beta1 receptor blocker used in treatment of several diseases of the
cardiovascular models. These are marketed under a marque Lopressor by Novartis, and Toprol (in the United states), Seleken or even Selokeen (elsewhere) by AstraZeneca and as Corvitol by Berlin-Chemie AG.
Properties:
cardioselective
lipophilic
forswearing intrinsic sympathomimetic activity (ISA)
while forgoing membrane stabilizing activity
short half-life must become taken at least twice daily or even SR preparations
Indications:
essential hypertension
arrhythmias
coronary heart disease (prevention of angina attacks)
secondary bar when the myocardial infarction
moo dosed professional assistance of a few forms of heart failure (see MERIT-HF learnSingle)
migraine prophylaxis
as an adjunct within coarse of action of hyperthyroidism
In the United States and most more countries, this medication is available single by prescription.
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